上海科敏生物销售VGLUT1 Antibody #12331 Cell Signaling，CST原装品质，*，订购VGLUT1 Antibody #12331 Cell Signaling，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：
货号：12331
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型：Polyclonal
规格：

抗体应用：

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on * sequence homology.
特异性/敏感度：VGLUT1 Antibody recognizes endogenous levels of total VGLUT1 protein.
来源及纯化方法：Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human VGLUT1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Glutamatergic neurons release glutamate, the most common excitatory neurotransmitter. Their synaptic vesicles are filled with glutamate by vesicular glutamate transporters, VGLUTs (1). VGLUT1, also called SLC17A7 for solute carrier family 17 member 7, was first identified as an inorganic phosphate transporter (2). Despite the absence of homology with neurotransmitter transporters, VGLUT1 was later demonstrated to be a glutamate transporter (1) specific to glutamatergic neurons (3). Closely related to VGLUT1, VGLUT2 and VGLUT3 are also involved in glutamate uptake into synaptic vesicles, but define different neuronal subpopulations (4,5). VGLUT1 and VGLUT2 are the most abundant isoforms. VGLUT1 is expressed in the cortex, hippocampus, and cerebellar cortex, while VGLUT2 is mostly found in the thalamus (6,7), and VGLUT3 is expressed in hair cells of the auditory pathway (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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