上海科敏生物销售TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling，CST原装品质，*，订购TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling，详情请咨询销售人员！
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产品名称：TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling
货号：12339
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型：Monoclonal
规格：

抗体应用：

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on * sequence homology.
特异性/敏感度：TPH-1 (D10C10) Rabbit mAb recognizes endogenous levels of total TPH-1 protein.
来源及纯化方法：Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TPH-1 protein.
抗体背景：

Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin (1) by converting tryptophan to 5-hydroxy-L-tryptophan (2). Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system (3). Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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