起订量:
人胆绿素还原酶A/BLVRA
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Recombinant Human Biliverdin Reductase A
人胆绿素还原酶A (BLVRA)
Catalogue Number ENZ-446
Synonyms:
Biliverdin reductase A, BVR A, Biliverdin-IX alpha-reductase, BLVRA, BLVR, BVR, BVRA.
Introduction:
Biliverdin reductase A (BLVRA) is a member of the gfo/idh/mocA family. BLVRA is an enzyme that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRA reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the simultaneous oxidation of a NADH or NADPH cofactor (Bilirubin + NAD(P)+ = biliverdin + NAD(P)H ).
BLVRA is a regulator for induction of activating transcription factor-2 and heme oxygenase-1. Furthermore, BLVRA enhances the role of HO-1 in cytoprotection and provides cytoprotection independent of heme degradation. In addition, Bilirubin while acting as a cytoprotective antioxidant is itself oxidized to biliverdin and subsequently recycled by biliverdin reductase back to bilirubin.
Description:
BLVRA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 295 amino acids (3-296 a.a. and Methionine at N-terminus) and having a molecular mass of 33.3kDa.
The BLVRA is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered colorless solution.
Formulation:
The BLVRA solution contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.
Stability:
BLVRA although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence:
MAEPERKFGV VVVGVGRAGS VRMRDLRNPH PSSAFLNLIG FVSRRELGSI DGVISLED ALSSQEVEVA YICSESSSHE DYIRQFLNAG KHVLVEYPMT LSLAAAQELW ELAEQKGKVL HEEHVELLME EFAFLKKEVV GKDLLKGSLL FTAGPLEEER FGFPAFSGIS RLTWLVSLFG
ELSLVSATLE ERKEDQYMKM TVCLETEKKS PLSWIEEKGP GLKRNRYLSF HFKSGSLENV PNVGVNKNIF LKDQNIFVQK LLGQFSEKEL AAEKKRILHC LGLAEEIQKY CCSRK.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
相关产品:
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Carbonic Anhydrase 2 人碳酸酐酶2 ENZ-420 Recombinant Human Carbonic Anhydrase 2
Carbonic Anhydrase-1 人碳酸酐酶1 ENZ-462 Recombinant Human Carbonic Anhydrase-1
rCarboxypeptidase-B 大鼠羧肽酶-B ENZ-475 Recombinant Rat Carboxypeptidase-B
CASP3, Active 人胱天蛋白酶-3 ENZ-369 Recombinant Human Caspase-3
CBR1 人羰基还原酶-1 ENZ-415 Recombinant Human Carbonyl Reductase-1
CBR3 人羰基还原酶-3 ENZ-428 Recombinant Human Carbonyl Reductase-3
CDC34 细胞周期调控因子34 ENZ-355 Recombinant Cell Division Cycle 34
CDO1 半胱氨酸双加氧酶 ENZ-449 Recombinant Human Cysteine Dioxygenase
COMT 人儿茶酚-O-甲基转移酶 ENZ-400 Recombinant Human Catechol-O-Methyltransferase
CRYZL1 人醌氧化还原酶样蛋白1 ENZ-481 Recombinant Human Quinone Oxidoreductase-like Protein 1
CTSD 人组织蛋白酶D ENZ-378 Recombinant Human Cathepsin-D
CTSL1 人组织蛋白酶L ENZ-377 Recombinant Human Cathepsin-L
Cyclophilin A 人亲环素-A ENZ-359 Recombinant Human Cyclophilin-A
Cyclophilin B 人亲环素-B ENZ-313 Recombinant Human Cyclophilin-B
Cyclophilin D 人亲环素-D ENZ-367 Recombinant Human Cyclophilin-D
Cyclophilin E 人亲环素-E ENZ-383 Recombinant Human Cyclophilin-E
Cyclophilin G 人亲环素-G ENZ-463 Recombinant Human Cyclophilin-G
CYP2D6 人细胞色素P450 2D6 ENZ-316 Recombinant Human Cytochrome P450 2D6
DAAO 人D -氨基酸氧化酶 ENZ-425 Recombinant Human D-Amino Acid Oxidase
DCTD 人Dcmp脱氨酶 ENZ-538 Recombinant Human dCMP Deaminase
DCXR 人二羰基/ L型木酮糖还原酶 ENZ-540 Recombinant Human Dicarbonyl/L-Xylulose Reductase
DDT ENZ-527 Recombinant Human D-Dopachrome Tautomerase
DHFR 人二氢叶酸还原酶 ENZ-443 Recombinant Human Dihydrofolate Reductase
DHPS ENZ-498 Recombinant Human Deoxyhypusine Synthase
DLD ENZ-502 Recombinant Human Dihydrolipoamide Dehydrogenase
DMGO 二甲基氧化酶 ENZ-318 Recombinant Dimethylglycine oxidase
DNase 人脱氧核糖核酸酶 ENZ-319 Recombinant Human Deoxyribonuclease I
bDNase 牛脱氧核糖核酸酶 ENZ-417 Bovine Deoxyribonuclease I
Dopa Decarboxylase 人多巴脱羧酶 ENZ-413 Recombinant Human Dopa Decarboxylase
DPP4 人二肽基肽酶4 ENZ-375 Recombinant Human Dipeptidyl-Peptidase 4
DPP4 人二肽基肽酶4 ENZ-382 Human Dipeptidyl-Peptidase 4
DsbA 二硫氧化还原酶 ENZ-276 Recombinant Disulfide Oxidoreductase
DsbC 二硫异构酶 ENZ-291 Recombinant Disulfide Bond Isomerase
dUTPase 耐高温磷酸酶 ENZ-281 Recombinant Thermostable dUTPase
ENO1 人烯醇化酶 ENZ-452 Recombinant Human Enolase-1
ENO2 人神经元特异性烯醇化酶 ENZ-324 Recombinant Human Neuronal Specific Enolase
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Enterokinase 人肠肽酶/肠激酶 ENZ-260 Recombinant Human Enteropeptidase/Enterokinase, Light Chain
bEnterokinase 牛肠肽酶/肠激酶 ENZ-311 Recombinant Bovine Enteropeptidase/Enterokinase
pEnterokinase 猪肠肽酶/肠激酶 ENZ-267 Porcine Enteropeptidase/Enterokinase
Esterase-D ENZ-447 Recombinant Human Esterase D,S-Formylglutathione Hydrolase
FBP1 人果糖-1,6-二磷酸酶1 ENZ-454 Recombinant Human Fructose-1,6-Bisphosphatase 1
FEN1 ENZ-468 Recombinant Human Flap Structure-Specific Endonuclease 1