Tyrosinase 酪氨酸酶（鼠单克隆抗体）

广州健仑生物科技有限公司

酪氨酸酶(Tyrosinase)又名单酚单氧化酶，催化酚类化合物(如酪氨酸)的氧化，广泛存在于动植物中。Tyrosinase在黑色素及其他色素的生成过程中起催化作用，存在于黑色体中。其基因的突变会导致I型眼-皮肤白化病（发病率1/17000）。该抗体特异性的表达于黑色素病变组织中，如恶性黑色素瘤、黑色素病变的神经纤维瘤，上皮来源的癌*不表达该抗体。

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Tyrosinase 酪氨酸酶（鼠单克隆抗体）

【产品介绍】

细胞定位：细胞浆

克隆号：T311

同型：IgG

适用组织：石蜡/冰冻

阳性对照：恶性黑色素瘤/皮肤色素痣

抗原修复：热修复（EDTA）

抗体孵育时间：30-60min

Tyrosinase

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【公司名称】 广州健仑生物科技有限公司
【市场部】     欧

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【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

艾布拉姆森癌症中心研究人员诺埃尔·弗雷说，“我们的试验结果说明，CTL019疗法可以对先前治疗失败的病人产生持久疗效，同时不必使用其他补充疗法”。这对于接受干细胞移植后癌症复发或者没有找到捐献者的病人来说是一个新的希望。
2014年7月美国食品和药物管理局赋予CTL019疗法“治疗学发现”称号，CTL019疗法是*个性化细胞疗法，在治疗效果上显示出重大优势，美国已在多家医院开始这种疗法的测试。
据日本《朝日新闻》16日报道，日本一化妆品公司宣布，成功使用iPS细胞(人工多能干细胞)实现了“返老还童”，将一位67岁日本男性的皮肤细胞恢复到和他本人36岁时的皮肤基本相同状态。
据悉，该男性自1980年以来，一直定期提供36岁-67岁间五个不同年龄段的皮肤细胞，并由京都大学ips细胞研究所将其转化为iPS细胞。
经化妆品公司分析，作为老化指标的染色体状态在五个年龄段均有所恢复，连67岁时采集的皮肤细胞也恢复到了和36岁时大致相同的状态。
该公司称，将使用此研究结果阐明皮肤老化机制。目前虽尚处于基础研究阶段，但从长远来看，这将会推动针对个人、不同敏感源的定制化妆品开发

Noel Frey, a researcher at the Abramson Cancer Center, said, "Our results demonstrate that CTL019 can produce long-lasting effects in previously unsuccessful patients without the need for other complementary therapies." This is a new hope for patients who have relapsed after stem cell transplantation or have not found a donor.
In July 2014, the US Food and Drug Administration awarded the title of "Therapeutics Discovery" to CTL019 Therapy. CTL019 Therapy is the first personalized cell therapy that shows major advantages in treatment effectiveness. The United States has started this therapy in several hospitals test.
According to Japan's "Asahi Shimbun" reported on the 16th, a cosmetics company in Japan announced the successful use of iPS cells (artificial pluripotent stem cells) to achieve "rejuvenation" will be a 67-year-old Japanese male skin cells and his return to 36 years old The skin is basically the same state.
It is reported that since 1980, the man has regularly provided skin cells of five different ages ranging from 36 to 67 years old and has been transformed into iPS cells by the ips cell research institute of Kyoto University.
Analyzed by the Cosmetics Company, the status of chromosomes as an indicator of aging recovered in all five age groups, and the skin cells collected at 67 were also restored to the same state as those at 36 years of age.
The company said it will use the results of this study to elucidate the mechanism of skin aging. Although it is still in the basic research phase, it will promote the development of customized cosmetics targeting individuals and sensitive sources in the long run