无创无束缚鼠肺功能WBP全身体积描记系统产品描述

塔望科技研发的无创无束缚鼠肺功能WBP全身体积描记系统（whole-body plethysmograph，WBP）可对清醒自由活动动物呼吸参数进行测量，如呼吸频率，潮气量，气道高反应性测试（Airway hyperresponsiveness，AHR）等。测试过程中，动物可以处于清醒自由状态，避免了创伤性气管切开及麻醉的影响，使实验过程更加简便，用于呼吸系统模型动物对药物等反应性研究，呼吸性药物的药理和毒理学研究，特别适合于大批量动物快速初筛试验，适合长期跟踪研究和重复性筛查。

无创无束缚鼠肺功能WBP全身体积描记系统产品特点

· 不需要做手术，操作简单

· 可多通道同时监测

· 可在动物在自然状态下呼吸的研究以及长期跟踪实验，适合进行药物初筛

· 具有药物气溶胶雾化模块

· 具有自动标定功能

· 具有饮水口和食物口，可进行长期连续监测

· 可选配测量心电、血压、体温、心率等指标，可与植入式遥测设备联合使用

· 具有分析软件，数据可保存至excel或txt格式

无创无束缚鼠肺功能WBP全身体积描记系统可选配的功能模块：

· 同步视频监测：同步的视频录像文件

· 咳嗽检测：通过软件自动监测咳嗽事件

· 其它生理指标测量：可在麻醉或清醒状态下测量心电、血压、体温、心率等指标，可与植入式遥测设备联合使用

无创无束缚鼠肺功能WBP全身体积描记系统检测参数

Ti：吸气时间（s）

Te：呼气时间（s）

PIF：最大吸气流速（ml/s）

PEF：最大呼气流速（ml/s）

Volbal：吸气时间/呼气时间

F：呼吸频率（次/min）

Vt：潮气量（ml）

Mv：分钟通气量（ml）

AV：累积体积（ml）

EF50：呼出50%气量时对应的呼气流速（ml/s）

EIP：吸气峰值压力（仅在侵入式法测量时有效）

EEP：呼气峰值压力（仅在侵入式法测量时有效）

TR：松弛时间

PenH：增强呼气间歇（enhanced pause）

Rpef：相对时间

无创无束缚鼠肺功能WBP全身体积描记系统适用领域

• 各种呼吸疾病研究，如：哮喘、肺纤维化、肺损伤、ARDS、肺癌等

• 安全药理：药物对呼吸系统的影响

• 睡眠呼吸：监测动物低通气、阻塞性呼吸暂停等

• 环境毒理：环境污染物对动物呼吸的影响
  

• 吸入式毒理：染毒物质对呼吸系统的毒性影响

• 高原医学：高原环境对呼吸系统的影响

• 其它需要对呼吸参数评价的场合

无创无束缚鼠肺功能WBP全身体积描记系统型号说明

无创无束缚鼠肺功能WBP全身体积描记系统用户名单

• 上海市中心医院	瑞金医院	复旦大学附属华山医院	上海药物所
  中国药科大学	广东药科大学	重庆医科大学	成都市第三人民医院
  北京中医药大学	中科院城市环境研究所	南京大学	四川大学华西医院
  苏州大学	中医药大学	安徽医科大学第一附属医院	青岛市市立医院
  兰州大学	南华大学	宁夏医科大学	......

无创无束缚鼠肺功能WBP全身体积描记系统

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