全身体积描记系统(兔、犬)产品描述

全身体积描记系统(兔、犬)（whole-bodyplethysmograph，WBP）可以对清醒自由活动的大动物进行肺功能及气道反应相关的测试，避免了创伤性气管切开术及麻醉的影响，使实验过程简便快捷，并适合长期跟踪研究。

塔望科技开发的全身体积描记系统，除了做小鼠、大鼠/豚鼠外，另外还提供大动物的测试舱，如兔子、犬、猴等。

全身体积描记系统(兔、犬)产品特点

· 适用动物：兔子、犬

· 不需要做手术，操作简单

· 可在动物在自然状态下呼吸的研究以及长期跟踪实验，适合进行药物初筛

· 具有药物气溶胶雾化模块

· 具有自动标定功能

· 可提供食槽，进行长期连续监测

· 可选配测量心电、血压、体温、心率等指标，可与植入式遥测设备联合使用

· 具有分析软件，数据可保存至excel或txt格式

全身体积描记系统(兔、犬)检测参数

Ti：吸气时间（s）

Te：呼气时间（s）

PIF：最大吸气流速（ml/s）

PEF：最大呼气流速（ml/s）

Volbal：吸气时间/呼气时间

F：呼吸频率（次/min）

Vt：潮气量（ml）

Mv：分钟通气量（ml）

AV：累积体积（ml）

EF50：呼出50%气量时对应的呼气流速（ml/s）

EIP：吸气峰值压力（仅在侵入式法测量时有效）

EEP：呼气峰值压力（仅在侵入式法测量时有效）

TR：松弛时间

PenH：增强呼气间歇（enhanced pause）

Rpef：相对时间

全身体积描记系统(兔、犬)适用领域

各种呼吸疾病研究，如：哮喘、肺纤维化、肺损伤、ARDS、肺癌等

安全药理：药物对呼吸系统的影响

睡眠呼吸：监测动物低通气、阻塞性呼吸暂停等

环境毒理：环境污染物对动物呼吸的影响

吸入式毒理：染毒物质对呼吸系统的毒性影响

高原医学：高原环境对呼吸系统的影响

其它需要对呼吸参数评价的场合

全身体积描记系统(兔、犬)型号说明

全身体积描记系统(兔、犬)用户名单

全身体积描记系统(兔、犬)相关文献

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[4]Yumei Zhou, Haihong Zhao, Tieshan Wang, Xiaoshan Zhao, Ji Wang and Qi Wang, " Anti-Inflammatory and Anti-asthmatic Effects of TMDCT Decoction in Eosinophilic Asthma Through Treg/ Th17 Balance" [J].Frontiers, 2022.819728:

[5]Yumei Zhou, Tieshan Wang, Xiaoshan Zhao, Ji Wang and Qi Wang, "Plasma Metabolites and Gut Microbiota Are Associated With T cell Imbalance in BALB/c Model of Eosinophilic Asthma" [J].Frontiers, 2022. 819747:

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[11]Mengjun Zhanga, Huiyang Jiang, Lan Wu,  Haoyu Lu, Hriday Bera, Xing Zhao, Xiong Guo, Xulu Liu, Dongmei Cun, Mingshi Yang. "Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment" [J]. Journal of Controlled Release, Volume 352

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[26]Yize Yin,Chaohui Mu,Jiahui Wang,Yixuan Wang, Wenmin Hu,Wenjing Zhu,Xinjuan Yu,Wanming Hao,Yuxin Zheng, Qinghai Li, Wei Han. CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function,[J]2023-07-26,DOI: 10.3390/toxics11080646

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