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8030> 人脐动脉平滑肌细胞 (HUASMC)提取于人脐动脉组织,第二代冻存。
血管平滑肌细胞是许多重大动脉疾病的细胞底物。血管平滑肌细胞的不断增长是动脉疾病发展的重要原因。研究表明血管平滑肌细胞表达ICAM-1和VCAM-1,它们能促进血管壁中炎症反应并与血管疾病的发展和稳定。体外培养的脐静脉内皮细胞做为研究血管的模型起着重要作用。并将对血管疾病的药理学和治疗继续提供信息。
人脐动脉平滑肌细胞 (HUASMC)提取于人脐动脉组织,第二代冻存。每管含有细胞数>5×105 cells/ml,此细胞通过对alpha-SMA 和Desmin免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。
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储存:液氮
运输:干冰
用途:科研
Vascular smooth muscle cell is the cellular substrate of most significant arterial diseases[1]. The increased growth potential of vascular smooth muscle cells represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate vascular smooth muscle cells expression ICAM-1 and VCAM-1 which may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular diseases [2]. In vitro culture of human VSMC as a model of vascular research has played a critical role and continue to provide information in the pharmacology and therapy of vascular diseases.
HUASMC from ScienCell Research Laboratories are isolated from human umbilical artery. HUASMC are cryopreserved at the end of secondary culture and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HUASMC are characterized by immunofluorescent method with antibodies to alpha-smooth muscle actin and desmin. HUASMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HUASMC are guaranteed to further expand for 15 population doublings in the conditions specified by ScienCell Research Laboratories.
Reference
[1] Schwartz, S. M., Campbell, G. R., Campbell, J. H. (1986) Replication of smooth muscle cells in vascular disease. Circ. Res. 58:427-444.
[2] Braun, M., Pietsch, P., Schror, K., Baumann, G., Felix, S. B. (1999) Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc. Res. 41:395-401.