Recombinant Human Her3/ErbB3 Protein, His tag

93282ES25Recombinant Human Her3/ErbB3 Protein, His tag

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2023-07-20 23:59:59
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供货周期:现货;货号:93282ES25;应用领域:医疗卫生,生物产业,制药;
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产品属性
供货周期
现货
货号
93282ES25
应用领域
医疗卫生,生物产业,制药
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翌圣生物科技(上海)股份有限公司

翌圣生物科技(上海)股份有限公司

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产品简介

Her3(Human epidermal growth factor Receptor 3), belongs to the protein kinase superfamily, the tyr protein kinase family, and the EGF receptor subfamily.

详细介绍

产品简介

 

Her3(Human epidermal growth factor Receptor 3), belongs to the protein kinase superfamily, the tyr protein kinase family, and the EGF receptor subfamily. This membrane-bound glycoprotein has a neuregulin-binding domain but no active kinase domain. It does not mediate intracellular signal transduction through protein phosphorylation, but can form heterodimerers with ErbB2 or other EGFR members responsible for tyrosine phosphorylation to generate receptor complexes and initiate pathways that lead to cell proliferation or differentiation.

 

性能参数

 

Synonyms

ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; ERBB3

Uniprot No.

P21860

Source

Recombinant Human HER3 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ser20-Thr643.

Molecular Weight

The protein has a predicted MW of 70.6 kDa. And it migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. 

Purity

> 95% as determined by SDS-PAGE.

Concentration

1mg/mL

Endotoxin

<0.01 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).

 

储存条件

 

The product should be stored at -25~-15℃ for 1 year from date of receipt.

2-7 days, 2 ~8 °C under sterile conditions after reconstitution.

3 months, -25~-15℃ under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

注意事项

 

1.Please operate with lab coats and disposable gloves,for your safety.

2.This product is for research use only.

 

产品数据

 

Ver. CN20230616

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